The 2024 women’s college basketball tournament is set to tip off as Iowa’s Caitlin Clark seeks to cap off her remarkable college career with a title, but standing in the Hawkeyes’ way is a field of 68 teams featuring, among others, an undefeated South Carolina squad as well as defending champions LSU and perennial powerhouses UConn and Stanford as well as fellow No.1 seeds USC and Texas.
Keep reading to see the pregame lines, spreads and totals from each of the opening round matchups. Catch every game from the First Four to the Final Four and the championship on ABC, ESPN, ESPN2, ESPNU and ESPNEWS.
Odds by ESPN BET 
as of publication time.
WEDNESDAY — First Four
(16) Presbyterian Blue Hose
(16) Sacred Heart Pioneers -8.5
Colonial Life Arena, Columbia, S.C. , 7 p.m. ET
Presbyterian: 20-14, 8-8 in Big South play
Sacred Heart: 23-9, 15-1 in Northeast play
Money line: Presbyterian (+280) Sacred Heart (-575) Total:115.5
BPI Projection: Sacred Heart by 8.5 points, straight up 78.3% of the time
(12) Columbia Lions -1.5
(12) Vanderbilt Commodores
Cassell Coliseum, Blacksburg, Va., 9 p.m. ET
Columbia: 23-6, 13-1 in Ivy play
Vanderbilt: 22-9, 9-7 in SEC play
Money line: Columbia (-115) Vanderbilt (-115) Total:138.5
BPI Projection: Columbia by 0.5 points, straight up 52% of the time
THURSDAY — First Four
(11) Arizona Wildcats -1.5
(11) Auburn Tigers
Gampel Pavilion, Storrs, Conn., 7 p.m. ET
Arizona: 17-15, 8-10 in Pac-12 play
Auburn: 20-11, 8-8 in SEC play
Money line: Arizona (-130) Auburn (-105) Total:127.5
BPI Projection: Arizona by 3.7 points, straight up 63.7% of the time
(16) UT Martin Skyhawks -1.5
(16) Holy Cross Crusaders
Carver-Hawkeye Arena, Iowa City, Iowa, 9 p.m. ET
UT Martin: 16-16, 11-7 in Ohio Valley play
Holy Cross: 19-12, 11-7 in PAT play
Money line: UT Martin (-120) Holy Cross (-115) Total:117.5
BPI Projection: Holy Cross by 3.1 points, straight up 61.4% of the time
FRIDAY
(9) Michigan State Spartans -3.5
(8) North Carolina Tar Heels
Colonial Life Arena, Columbia, S.C. , 11:30 a.m. ET
Michigan State: 22-8, 12-6 in Big Ten play
North Carolina: 19-12, 11-7 in ACC play
Money line: Michigan State (-200) North Carolina (+140) Total:142.5
BPI Projection: Michigan State by 1.5 points, straight up 55.8% of the time
(15) Maine Black Bears
(2) Ohio State Buckeyes -26.5
Value City Arena, Columbus, Ohio, 12 p.m. ET
Maine: 24-9, 14-2 in America East play
Ohio State: 25-5, 16-2 in Big Ten play
Money line: Maine (+2800) Ohio State () Total:133.5
BPI Projection: Ohio State by 25.3 points, straight up 97.9% of the time
(11) Middle Tennessee Blue Raiders
(6) Louisville Cardinals -5.5
Pete Maravich Assembly Center, Baton Rouge, La., 1:30 p.m. ET
Middle Tennessee: 29-4, 16-0 in C-USA play
Louisville: 24-9, 12-6 in ACC play
Money line: Middle Tennessee (+175) Louisville (-250) Total:129.5
BPI Projection: Louisville by 3.6 points, straight up 63.3% of the time
Sacred Heart/Presbyterian
(1) South Carolina Gamecocks
Colonial Life Arena, Columbia, S.C. , 2 p.m. ET
South Carolina: 32-0, 16-0 in SEC play
Betting lines TBD
(10) Richmond Spiders
(7) Duke Blue Devils -10.5
Value City Arena, Columbus, Ohio, 2:30 p.m. ET
Richmond: 29-5, 16-2 in A-10 play
Duke: 20-11, 11-7 in ACC play
Money line: Richmond (+400) Duke (-900) Total:125.5
BPI Projection: Duke by 10 points, straight up 82% of the time
(16) Drexel Dragons
(1) Texas Longhorns -35.5
Moody Center, Austin, Texas, 3 p.m. ET
Drexel: 18-14, 10-8 in Coastal play
Texas: 30-4, 14-4 in Big 12 play
Money line: Drexel (+2800) Texas () Total:121.5
BPI Projection: Texas by 35.2 points, straight up 99.5% of the time
(13) Marshall Thundering Herd
(4) Virginia Tech Hokies -12.5
Cassell Coliseum, Blacksburg, Va., 3:30 p.m ET
Marshall: 26-6, 17-1 in Sun Belt play
Virginia Tech: 24-7, 14-4 in ACC play
Money line: Marshall (+500) Virginia Tech (-1400) Total:150.5
BPI Projection: Virginia Tech by 19.6 points, straight up 95.1% of the time
(14) Rice Owls
(3) LSU Tigers -27.5
Pete Maravich Assembly Center, Baton Rouge, La., 4 p.m. ET
Rice: 19-14, 9-9 in American play
LSU: 28-5, 13-3 in SEC play
Money line: Rice (+2800) LSU () Total:147.5
BPI Projection: LSU by 25.5 points, straight up 97.9% of the time
(13) Portland Pilots
(4) Kansas State Wildcats -23.5
Bramlage Coliseum, Manhattan, Kan., 4:30 p.m. ET
Portland: 21-12, 9-6 in WCC play
Kansas State: 25-7, 12-5 in Big 12 play
Money line: Portland (+1600) Kansas State (-20000) Total:128.5
BPI Projection: Kansas St by 20.6 points, straight up 95.8% of the time
(9) Florida State Seminoles
(8) Alabama Crimson Tide -3.5
Moody Center, Austin, Texas, 5:30 p.m. ET
Florida State: 23-10, 12-6 in ACC play
Alabama: 23-9, 10-6 in SEC play
Money line: Florida State (+135) Alabama (-190) Total:147.5
BPI Projection: Alabama by 1.5 points, straight up 55.8% of the time
Vanderbilt/Columbia
(5) Baylor Bears
Cassell Coliseum, Blacksburg, Va., 6 p.m. ET
Baylor: 24-7, 12-6 in Big 12 play
Betting lines TBD
(12) Drake Bulldogs
(5) Colorado Buffaloes -9.5
Bramlage Coliseum, Manhattan, Kan., 7 p.m. ET
Drake: 28-5, 19-1 in MVC play
Colorado: 22-9, 11-7 in Pac-12 play
Money line: Drake (+350) Colorado (-700) Total:149.5
BPI Projection: Colorado by 13.2 points, straight up 88% of the time
(10) Maryland Terrapins
(7) Iowa State Cyclones -1.5
Maples Pavilion, Stanford, Calif., 7:30 p.m. ET
Maryland: 19-13, 9-9 in Big Ten play
Iowa State: 20-11, 11-6 in Big 12 play
Money line: Maryland (-105) Iowa State (-130) Total:151.5
BPI Projection: Maryland by 0.2 points, straight up 50.9% of the time
(14) Eastern Washington Eagles
(3) Oregon State Beavers -18.5
Gill Coliseum, Corvallis, Ore., 8 p.m. ET
Eastern Washington: 29-5, 16-2 in Big Sky play
Oregon State: 24-7, 12-6 in Pac-12 play
Money line: Eastern Washington (+1200) Oregon State (-10000) Total:125.5
BPI Projection: Oregon State by 17.9 points, straight up 93.8% of the time
(15) Norfolk State Spartans
(2) Stanford Cardinal -35.5
Maples Pavilion, Stanford, Calif., 10 p.m. ET
Norfolk State: 27-5, 13-1 in MEAC play
Stanford: 28-5, 15-3 in Pac-12 play
Money line: Norfolk State (+2800) Stanford () Total:125.5
BPI Projection: Stanford by 31.2 points, straight up 99.1% of the time
(11) Texas A&M Aggies
(6) Nebraska Cornhuskers -3.5
Gill Coliseum, Corvallis, Ore., 10:30 p.m. ET
Texas A&M: 19-12, 6-10 in SEC play
Nebraska: 22-11, 11-7 in Big Ten play
Money line: Texas A&M (+130) Nebraska (-180) Total:128.5
BPI Projection: Nebraska by 2.3 points, straight up 58.5% of the time
SATURDAY
(11) Green Bay Phoenix
(6) Tennessee Lady Volunteers -7.5
Reynolds Coliseum, Raleigh, N.C., 12 p.m. ET
Green Bay: 27-6, 17-3 in Horizon play
Tennessee: 19-12, 10-6 in SEC play
Money line: Green Bay (+240) Tennessee (-425) Total:136.5
BPI Projection: Tennessee by 5.8 points, straight up 70.7% of the time
(14) Jackson State Tigers
(3) UConn Huskies -33.5
Gampel Pavilion, Storrs, Conn., 1 p.m. ET
Jackson State: 26-6, 18-0 in SWAC play
UConn: 29-5, 18-0 in Big East play
Money line: Jackson State (+2800) UConn () Total:135.5
BPI Projection: UConn by 30.6 points, straight up 99% of the time
(13) Fairfield Stags
(4) Indiana Hoosiers
Simon Skjodt Assembly Hall, Bloomington, Ind., 1:30 p.m. ET
Fairfield: 31-1, 20-0 in MAAC play
Indiana: 24-5, 15-3 in Big Ten play
Betting lines TBD
BPI Projection: Indiana by 23 points, straight up 97% of the time
(9) Michigan Wolverines
(8) Kansas Jayhawks -1.5
Galen Center, Los Angeles, CA, 2 p.m. ET
Michigan: 20-13, 9-9 in Big Ten play
Kansas: 19-12, 11-7 in Big 12 play
Money line: Michigan (-110) Kansas (-125) Total:129.5
BPI Projection: Kansas by 1.3 points, straight up 54.7% of the time
(15) Kent State Golden Flashes
(2) Notre Dame Fighting Irish -31.5
Purcell Pavilion, South Bend, Ind., 2:15 p.m. ET
Kent State: 21-10, 12-5 in MAC play
Notre Dame: 26-6, 13-5 in ACC play
Money line: Kent State (+2800) Notre Dame () Total:139.5
BPI Projection: Notre Dame by 26.1 points, straight up 98.1% of the time
(14) Chattanooga Mocs
(3) NC State Wolfpack -27.5
Reynolds Coliseum, Raleigh, N.C., 2:30 p.m. ET
Chattanooga: 28-4, 13-1 in SoCon play
NC State: 27-6, 13-5 in ACC play
Money line: Chattanooga (+2800) NC State () Total:120.5
BPI Projection: NC State by 24 points, straight up 97.4% of the time
Holy Cross/UT Martin
(1) Iowa Hawkeyes
Carver-Hawkeye Arena, Iowa City, Iowa, 3 p.m. ET
Iowa: 29-4, 15-3 in Big Ten play
Betting lines TBD
Auburn/Arizona
(6) Syracuse Orange
Gampel Pavilion, Storrs, Conn., 3:30 p.m. ET
Syracuse: 23-7, 13-5 in ACC play
Betting lines TBD
(12) Florida Gulf Coast Eagles
(5) Oklahoma Sooners -7.5
Simon Skjodt Assembly Hall, Bloomington, Ind., 4 p.m. ET
Florida Gulf Coast: 29-4, 16-0 in ASUN play
Oklahoma: 22-9, 15-3 in Big 12 play
Money line: Florida Gulf Coast (+230) Oklahoma (-400) Total:145.5
BPI Projection: Oklahoma by 4.8 points, straight up 67.3% of the time
(16) Texas A&M-Corpus Christi Islanders
(1) USC Trojans -32.5
Galen Center, Los Angeles, CA, 4:30 p.m. ET
Texas A&M-Corpus Christi: 23-8, 14-4 in Southland play
USC: 26-5, 13-5 in Pac-12 play
Money line: Texas A&M-Corpus Christi (+2800) USC () Total:126.5
BPI Projection: USC by 30.2 points, straight up 99% of the time
(10) Marquette Golden Eagles
(7) Ole Miss Rebels -5.5
Purcell Pavilion, South Bend, Ind., 4:45 p.m. ET
Marquette: 23-8, 11-7 in Big East play
Ole Miss: 23-8, 12-4 in SEC play
Money line: Marquette (+200) Ole Miss (-285) Total:123.5
BPI Projection: Ole Miss by 2.1 points, straight up 57.9% of the time
(9) Princeton Tigers
(8) West Virginia Mountaineers
Carver-Hawkeye Arena, Iowa City, Iowa, 5:30 p.m. ET
Princeton: 25-4, 13-1 in Ivy play
West Virginia: 24-7, 12-6 in Big 12 play
Betting lines TBD
BPI Projection: West Virginia by 2.7 points, straight up 60.2% of the time
(10) UNLV Lady Rebels
(7) Creighton Bluejays -1.5
Pauley Pavillion, Los Angeles, 7 p.m. ET
UNLV: 30-2, 17-1 in MW play
Creighton: 25-5, 15-3 in Big East play
Money line: UNLV (+100) Creighton (-135) Total:141.5
BPI Projection: Creighton by 1.7 points, straight up 56.5% of the time
(13) UC Irvine Anteaters
(4) Gonzaga Bulldogs -22.5
McCarthey Athletic Center, Spokane, Wash., 7:30 p.m. ET
UC Irvine: 23-8, 15-4 in Big West play
Gonzaga: 30-3, 16-0 in WCC play
Money line: UC Irvine (+1600) Gonzaga (-20000) Total:128.5
BPI Projection: Gonzaga by 22.6 points, straight up 96.8% of the time
(15) California Baptist Lancers
(2) UCLA Bruins
Pauley Pavillion, Los Angeles, 9:30 p.m. ET
California Baptist: 28-3, 18-2 in WAC play
UCLA: 25-6, 13-5 in Pac-12 play
Betting lines TBD
BPI Projection: UCLA by 29.6 points, straight up 98.9% of the time
(12) South Dakota State Jackrabbits
(5) Utah Utes -7.5
McCarthey Athletic Center, Spokane, Wash., 10 p.m. ET
South Dakota State: 27-5, 16-0 in Summit League play
Utah: 22-10, 11-7 in Pac-12 play
Money line: South Dakota State (+240) Utah (-425) Total:136.5
BPI Projection: Utah by 11.4 points, straight up 85% of the time
